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The Forbury Clinic

Uromune UTI Vaccine in London

Uromune is a sublingual treatment used to help prevent recurrent urinary tract infections. Rather than treating an infection once it has developed, it is designed to support the immune system’s response to the bacteria commonly associated with UTIs.

It may be considered as an alternative to repeated or long-term antibiotics for suitable people with recurrent infections.

  • A vaccine, not an antibiotic
  • Pioneered in the UK
    A sublingual UTI vaccine
    Aims to reduce recurrence
    Prescribed after specialist assessment
    Part of a consultant-led plan

What is the Uromune UTI vaccine?

Uromune is a UTI vaccine, also known as MV140. It is designed to help prevent recurrent urinary tract infections by supporting the body’s immune defences, rather than treating an infection with antibiotics once it is already present.

It is taken as a daily spray under the tongue, usually as a three-month course. Uromune contains inactivated forms of bacteria commonly associated with UTIs. The treatment is intended to help the immune system recognise and respond to these bacteria more effectively.

This may be particularly relevant for people who have recurrent infections and would like to discuss an approach that may reduce their reliance on antibiotics over time.

Uromune can be considered for women and men with recurrent UTIs. It may also be discussed in some more complex cases, including where catheter use or a neurogenic bladder, meaning bladder dysfunction caused by a problem affecting the nerves, may be contributing to infection risk.

Uromune is an unlicensed medicine in the UK. This means it is prescribed on a named-patient basis following assessment by a specialist consultant. Your consultant will explain what this means, why it may or may not be appropriate for you and the potential benefits, limitations and risks.

Supporting your natural defences

How it works

Uromune is designed to work with the body’s immune system to help reduce recurrent infections.

Targets bacteria commonly linked to UTIs

The treatment is based on inactivated bacteria that are commonly associated with urinary tract infections.

Prompts an immune response

Taken under the tongue, it is designed to support the immune response involved in protecting the urinary tract.

Aims to reduce recurrence

The goal is to reduce the frequency of UTIs over time, as part of a broader, individual prevention plan.

Who the UTI vaccine may suit

The Uromune UTI vaccine may be considered for people who:

  • Experience recurrent urinary tract infections
  • Would like to discuss an alternative to repeated or long-term antibiotics
  • Have had repeated infections despite usual prevention measures
  • Have more complex UTIs, including those associated with catheters or a neurogenic bladder
  • Have been assessed as suitable by a specialist consultant

What to expect

  1. Specialist assessment
    Your consultant will discuss your history of UTIs, previous tests and treatments, and any factors that may be contributing to recurrence. They will also explain the unlicensed, named-patient basis for prescribing Uromune.
  2. Three-month course
    If Uromune is appropriate, it is taken as a daily spray under the tongue, usually for around three months. Treatment is completed at home.
  3. Review and follow-up
    Your consultant will review how you respond to treatment and discuss any appropriate next steps. In some circumstances, a repeat course may be considered in the future.

Uromune has been evaluated in clinical studies and long-term follow-up data.

The evidence

Published research reports that:

56%
Around 56 to 58 percent of patients remaining free of UTIs during a study period compared with approximately 25 percent on placebo
UTI Episodes
A reduction in median UTI episodes from three to none during the study period
Infections
Sustained reductions in infections over several years of follow-up in real-world settings
Safety
A strong safety and tolerability profile in published data

Long-term UK follow-up has shown that some patients remain infection-free for several years, while others experience fewer and less severe episodes.

Individual outcomes vary. Your consultant will explain what is realistic for your situation.

Why choose The Forbury Clinic for a UTI vaccine consultation in London?

Why The Forbury Clinic
1

Alternative to repeated antibiotics

Uromune is designed to support UTI prevention, rather than relying only on antibiotics to treat each new infection.

2

Part of a wider prevention plan

Your consultant will consider possible causes of recurrent infections, including bladder emptying, menopausal changes and other urological factors, rather than viewing Uromune in isolation.

3

Evidence-informed care

Clinical studies have explored the use of Uromune in people with recurrent UTIs. Your consultant will explain what the evidence may mean for your individual circumstances.

4

Specialist assessment in London

Uromune is prescribed only after a full consultant assessment at The Forbury Clinic London.

Frequently asked questions

Is Uromune really a vaccine?

Uromune is commonly described as a UTI vaccine because it is designed to stimulate an immune response to bacteria associated with urinary tract infections. It is taken under the tongue as a spray rather than given as an injection.

Is Uromune available in the UK?

Uromune is available in the UK as an unlicensed medicine on a named-patient basis. A specialist consultant must assess whether it is appropriate and prescribe it for the individual patient.

How effective is Uromune?

Some clinical studies have reported a reduction in recurrent UTIs for people treated with Uromune. However, outcomes vary and treatment cannot guarantee that infections will stop. Your consultant will discuss what may be realistic based on your infection history and wider health.

How is Uromune different from antibiotics?

Antibiotics are used to treat bacterial infections that are already present. Uromune is intended to help prevent recurrent UTIs by supporting the immune system’s response to bacteria associated with infection.

Can I have Uromune without seeing a specialist?

No. As Uromune is an unlicensed medicine in the UK, it can only be prescribed on a named-patient basis following a specialist assessment.

Reviewed by Mr. Steve Foley
Mr. Foley is a Consultant Urological Surgeon with a focus on female urology and male incontinence.
Last reviewed: 17 Sep 2026.

Discuss Uromune for recurrent UTIs

Book an Appointment

If urinary tract infections keep coming back, our consultant urologists can assess possible causes and explain whether Uromune may be an appropriate part of your prevention plan.

  • Appointment
    Book a consultation
  • Reception
    0118 920 7055
  • Location

    The Forbury Clinic London, 45 Queen Anne St, London, W1G 9J

Treatment suitability is determined following consultation with a specialist. Individual results and recommendations vary.
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