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The Forbury Clinic

Perovial Treatment for Peyronie’s Disease, London

Perovial is a minimally invasive injectable treatment for Peyronie’s disease. It uses high-purity hyaluronic acid, injected directly into the plaque, to support treatment during the active phase of the condition.

It may be considered as a non-surgical option for suitable men experiencing changing curvature or pain during erections.

  • EMA-approved injectable device
    Course of 10 injections
    One injection per week
    High‑purity hyaluronic acid
    Carried out in clinic by a specialist

What is Perovial?

Perovial is an injectable medical device containing high-purity hyaluronic acid. It is used in the active phase of Peyronie’s disease, when curvature or pain may still be changing.

Peyronie’s disease occurs when fibrous scar tissue, known as plaque, develops inside the penis. This can lead to a bend or curve during erections, pain, changes in sexual function and difficulty with confidence or intimacy.

Perovial is injected directly into the plaque. The treatment aims to support tissue flexibility and may help manage pain and curvature in suitable men during the active phase.

Hyaluronic acid occurs naturally in the body’s tissues and is able to retain water. In this setting, it is used as part of a specialist-led treatment approach for Peyronie’s disease.

Perovial is one of several treatment options for Peyronie’s disease. Your consultant will assess whether you are in the active phase and explain whether it may be appropriate for you.

Three ways hyaluronic acid helps

How it works

Perovial is delivered as a series of injections into the plaque.

Antioxidant action

Hyaluronic acid may help address oxidative stress, which can be involved in the inflammatory processes associated with Peyronie’s disease.

Anti‑fibrotic effect

The treatment is intended to help limit the collagen activity associated with plaque formation and loss of tissue flexibility.

Hydration and tissue flexibility

Hyaluronic acid attracts and retains water, which may help support the flexibility of tissue affected by plaque.

Who Perovial may suit

Perovial may be considered for men with Peyronie’s disease in the active phase, particularly those experiencing:

  • Increasing or changing penile curvature
  • Pain during erections
  • Difficulties with sexual function or intimacy
  • Concerns about the impact on confidence and relationships
  • A preference to discuss non-surgical treatment options
  • A wish to seek advice while the condition is still changing

What to expect

  1. Initial consultation
    Your consultant will assess your symptoms, examine the plaque where appropriate and establish whether Peyronie’s disease is in the active phase.
  2. Weekly injections
    Treatment is delivered as a course of 10 injections, usually given one week apart. The injections are placed directly into the plaque during a clinic appointment.
  3. Review and monitoring
    Your consultant will review your symptoms, including pain, curvature and sexual function, throughout the treatment course.

Why choose The Forbury Clinic for Perovial in London?

Why The Forbury Clinic
1

A non-surgical treatment option

Perovial may be considered as an alternative to surgery for suitable men in the active phase of Peyronie’s disease.

2

Specialist-led assessment

Your consultant will establish whether the treatment is appropriate based on the stage of Peyronie’s disease and the symptoms affecting you.

3

Careful monitoring throughout

Your response to treatment is reviewed over the course, allowing your consultant to discuss progress and any appropriate next steps.

4

Discreet, consultant-led care in London

Peyronie’s disease can be difficult to discuss. Our team provides confidential care at The Forbury Clinic, 45 Queen Anne St, London W1G 9JF.

From assessment to improvement

Perovial is most effective when used during the active phase of Peyronie’s disease.

Not every man with Peyronie’s disease is a candidate for injectable treatment. In stable or long‑standing curvature, surgical options may be more appropriate.

Treatment decisions are based on disease stage, severity and personal goals.

Frequently asked questions

What is Peyronie’s disease?

Peyronie’s disease is a condition where fibrous scar tissue, called plaque, forms inside the penis. This can cause curvature during erections, pain, a firm area beneath the skin or changes in erectile function.

How many Perovial sessions will I need?

A course usually involves 10 injections, given one week apart. Your consultant will confirm the recommended plan during your consultation.

Is Perovial treatment painful?

The injections are placed directly into the plaque and some discomfort can occur. Your clinician will explain what the appointment involves and the steps taken to keep you as comfortable as possible.

Is Perovial right for me?

Perovial may be considered for suitable men in the active phase of Peyronie’s disease. A consultant assessment is needed to establish whether it is appropriate for your symptoms and the stage of the condition.

Is Perovial an alternative to surgery?

It may be a non-surgical option for some men, particularly during the active phase. If curvature becomes stable and continues to make sexual activity difficult, other treatments, including surgery, may need to be discussed.

Reviewed by Mr. Steve Foley
Mr. Foley is a Consultant Urological Surgeon with a focus on female urology and male incontinence.
Last reviewed: 11 Sep 2026.

Speak to our team about Perovial

Book an Appointment

If Peyronie’s disease is causing curvature, pain or concern about sexual function, our consultant urologists can explain whether Perovial may be an appropriate option for you.

  • Appointment
    Book a consultation
  • Reception
    0118 920 7055
  • Location

    The Forbury Clinic London, 45 Queen Anne St, London, W1G 9J

Treatment suitability is determined following consultation with a specialist. Individual results and recommendations vary.
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