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The Forbury Clinic

Advanced Syfovre (Pegcetacoplan) Treatment*

Discover advanced treatment for retinal conditions with Syfovre (Pegcetacoplan) at The Forbury Clinic. Submit an enquiry for a consultation and learn about our innovative treatment options.

*Please note that this treatment is not yet available and is awaiting NICE guidance. Submit an enquiry to join our waitlist for further information as it becomes available.

Overview

Syfovre (Pegcetacoplan) is a cutting-edge treatment designed to address serious retinal conditions, including geographic atrophy secondary to age-related macular degeneration (AMD). This groundbreaking medication works by inhibiting the complement pathway, helping to preserve vision and slow disease progression. Early and effective treatment with Syfovre is essential to maintaining eye health and preventing further complications. At The Forbury Clinic, we specialise in providing personalised care and the latest techniques in administering Syfovre. Contact us today to schedule a consultation and explore our treatment options.

What is Syfovre (Pegcetacoplan)?

Syfovre (Pegcetacoplan) is an innovative medication used to treat geographic atrophy (GA), a severe form of age-related macular degeneration (AMD). Geographic atrophy is characterised by the progressive degeneration of retinal cells, leading to vision loss. Syfovre works by inhibiting the complement system, which is part of the immune response that can contribute to retinal damage. By targeting and modulating this pathway, Syfovre helps to slow the progression of GA and preserve central vision. Common symptoms of geographic atrophy include blurry vision, difficulty reading, and dark or empty areas in the center of vision.

Causes and Risk Factors

Geographic atrophy and other conditions treated with Syfovre are influenced by various factors:

  • Age:

    The risk of developing geographic atrophy increases significantly with age, particularly in individuals over 60.

  • Genetics:

    A family history of age-related macular degeneration can increase the likelihood of developing GA.

  • Lifestyle Factors:

    Smoking and poor diet can contribute to the development and progression of AMD and GA.

  • Cardiovascular Health:

    Conditions such as hypertension and high cholesterol can exacerbate retinal damage.

  • Inflammation:

    Chronic inflammation and immune system dysregulation can play a role in the progression of GA.

Understanding these causes and risk factors helps in the early diagnosis and effective management of conditions treated with Syfovre, improving patient outcomes.

Diagnosis

Diagnosing geographic atrophy and other conditions treated with Syfovre involves a comprehensive evaluation at The Forbury Clinic. The diagnostic process includes:

  • Initial Consultation: Discussing symptoms, medical history, and potential risk factors with a specialist.
  • Visual Acuity Test: Assessing the clarity and sharpness of your vision.
  • Dilated Eye Exam: Using drops to dilate the pupils and examine the retina and macula for signs of geographic atrophy.
  • Optical Coherence Tomography (OCT): Imaging the retina to detect areas of thinning and degeneration.
  • Fundus Autofluorescence (FAF): Imaging technique to highlight areas of retinal damage and atrophy.
  • Genetic Testing: In some cases, testing for genetic markers associated with AMD and GA may be recommended.

These steps ensure a thorough and accurate diagnosis, aiding in the development of an effective treatment plan.

Treatment Options

Based on the diagnosis, Syfovre (Pegcetacoplan) is administered as part of a comprehensive treatment plan for geographic atrophy and other related conditions:

Non-Surgical Options
  • Syfovre Injections:

    Administered directly into the eye to inhibit the complement system and slow the progression of GA.

  • Nutritional Supplements:

    Recommending AREDS2 supplements to support retinal health.

Combination Therapies
  • Antioxidant Therapy:

    Encouraging a diet rich in antioxidants to support overall eye health.

  • Lifestyle Modifications:

    Advising smoking cessation, healthy diet, and regular exercise to manage risk factors.

Follow-Up Care
  • Regular Monitoring:

    Scheduling frequent check-ups to monitor treatment progress and adjust the treatment plan as needed.

  • Additional Injections:

    Administering further Syfovre injections based on the patient’s response to treatment and disease progression.

At The Forbury Clinic, our multidisciplinary team ensures that each patient receives the most appropriate and effective treatment, tailored to their specific needs and health goals.

Managing Geographic Atrophy with Syfovre

Managing geographic atrophy with Syfovre involves a combination of medical treatments and lifestyle adjustments to control symptoms and improve overall quality of life. At The Forbury Clinic, we provide comprehensive care and guidance to help manage these conditions:

  • Healthy Diet:

    Encouraging a diet rich in fruits, vegetables, and omega-3 fatty acids.

  • Regular Exercise:

    Promoting physical activity to improve overall health and blood flow to the eyes.

  • Routine Eye Exams:

    Scheduling frequent check-ups to monitor eye health and adjust treatment as necessary.

  • Eye Protection:

    Wearing sunglasses with UV protection to prevent further retinal damage.

These management strategies aim to complement medical treatments and provide a holistic approach to preserving vision and overall well-being.

Complications and Prognosis

While Syfovre is effective in managing geographic atrophy, it is important to be aware of potential complications and the prognosis:

Complications:

  • Eye Infections: Risk of infection at the injection site.
  • Increased Intraocular Pressure: Elevated pressure inside the eye.
  • Retinal Detachment: Although rare, this can occur following intravitreal injections.

Prognosis:

The prognosis for patients receiving Syfovre treatment is generally positive, with many individuals experiencing significant slowing of disease progression and preservation of vision. Regular follow-ups and ongoing management are crucial to prevent complications and ensure optimal eye health.

Why Choose The Forbury Clinic?

Choosing The Forbury Clinic for your Syfovre treatment ensures you receive exceptional care from a team of experienced specialists. Our clinic is renowned for its expert medical staff who are dedicated to diagnosing and treating retinal conditions with precision and compassion. We use state-of-the-art diagnostic tools and the latest medical advancements to provide accurate diagnoses and innovative treatments tailored to your specific needs. Our patient-centered approach prioritises your comfort, privacy, and overall well-being, offering comprehensive support throughout your treatment journey. At The Forbury Clinic, you can trust that you are in capable hands, with a dedicated team committed to helping you achieve optimal eye health and a better quality of life.