Genetic Testing for Prostate Cancer
Discover how genetic testing for prostate cancer can assess your inherited risk and guide early screening or treatment.
What is Genetic Testing for Prostate Cancer?
Genetic testing for prostate cancer analyses your DNA to identify inherited mutations that may increase your risk of developing the disease. It provides vital information that can support decisions about screening, risk reduction and treatment planning.
Certain gene changes, such as in BRCA1, BRCA2 and HOXB13, are linked with a significantly higher risk of aggressive or early-onset prostate cancer. Understanding whether you carry these mutations can also offer valuable insights for your family, as these alterations can be passed down through generations.
Why is Genetic Testing Important for Prostate Cancer?
Genetic testing helps identify men at higher risk of prostate cancer, especially those who may develop it earlier or more aggressively. It can guide decisions on early screening, active surveillance or preventive strategies. In men already diagnosed with prostate cancer, genetic information can inform treatment choices, including eligibility for targeted therapies.
How our Genetic Testing for Prostate Cancer Works
Your consultant will begin by reviewing your personal and family history to assess whether genetic testing is appropriate. If so, they’ll explain the process and provide either a saliva or blood sample kit. Many patients choose to complete the test at home using a simple saliva kit, which can be posted directly to the laboratory in a pre-paid envelope.
The sample is analysed in a certified laboratory to check for inherited mutations linked to prostate cancer, including BRCA1, BRCA2 and HOXB13. Additional genes may be assessed if clinically relevant. Results are typically ready within two to four weeks.
Once your results are available, you will receive a clear and personalised report. If any significant mutations are found, your consultant will explain what this means for you and your family, offering guidance on next steps such as increased screening, treatment planning or family testing. We also work closely with clinical geneticists to ensure you receive the right support throughout your care.
Who Should Consider Genetic Testing for Prostate Cancer?
Genetic testing for prostate cancer may be especially helpful if you have:
- A personal history of prostate cancer, particularly if diagnosed before age 55 or with aggressive features
- A close relative (father, brother, son) diagnosed with prostate cancer
- A family history of cancers linked to inherited risk, such as breast, ovarian or pancreatic cancer
- Known mutations in BRCA1, BRCA2, HOXB13 or Lynch syndrome genes in your family
- Ashkenazi Jewish ancestry, where BRCA mutations are more common
If you’re unsure whether testing is right for you, our consultants will offer personalised guidance based on your history and concerns.
What’s the Difference Between Inherited and Sporadic Prostate Cancer?
Most prostate cancers are sporadic, therefore they occur by chance, without a known inherited cause. Inherited prostate cancer, however, is caused by mutations passed down through families. These inherited forms often appear at a younger age and may be more aggressive. Genetic testing helps identify men with inherited risk, allowing earlier monitoring and targeted care.
What is Lynch Syndrome and How is it Related to Prostate Cancer?
Lynch syndrome is an inherited condition caused by mutations in DNA repair genes, such as MSH2 or MSH6. While it’s best known for increasing the risk of bowel and uterine cancers, it also raises the risk of prostate cancer, particularly early and aggressive types. Men with Lynch syndrome may benefit from earlier, regular prostate cancer screening.
Genetic Testing for Prostate Cancer FAQs
- Is genetic testing painful?
No. Testing involves a simple blood or saliva sample and is completely non-invasive.
- Can I do the test from home?
Yes, our service is fully home-based. We will send you a simple saliva collection kit, which you return to the laboratory in a prepaid envelope.
- How long does it take to get the results?
Results are typically available within 4–6 weeks. A detailed report will be sent to you directly.
- What can genetic testing tell me about my health?
It can identify genetic markers linked to certain inherited conditions, offering insights into your risk and helping guide treatment or preventive care.
- Who should consider genetic testing?
Anyone with a family history of genetic disorders or certain cancers, or those looking for personalised insights into long-term health, fertility, or wellness.
- If my test is positive, does it mean I will get cancer?
No. A positive result means you have a higher risk, but it does not guarantee that you will develop cancer. It provides valuable information to guide screening, prevention and treatment decisions.
- What if my results show a genetic mutation?
You’ll receive expert support and a personalised care plan. This may include enhanced screening, preventive strategies or referrals for family members to consider testing.
Why Choose The Forbury Clinic?
The Forbury Clinic provides private genetic testing with accuracy, efficiency and patient comfort in mind. Our expert clinicians use the latest diagnostic technology to ensure reliable results, helping you to understand your body and take control of your health. We prioritise a smooth experience with minimal waiting times, allowing for fast testing and efficient result processing.