Genetic Testing for Pancreatic Cancer
Understand your inherited risk of pancreatic cancer through expert-led genetic testing. Fast results, clear guidance and personalised support.
What is Genetic Testing for Pancreatic Cancer?
Genetic testing for pancreatic cancer analyses your DNA to detect inherited mutations that may increase your risk of developing the disease. These tests are designed to identify specific gene changes passed down through families that can contribute to pancreatic cancer development.
By understanding your inherited risk, genetic testing offers insights not just for your own health but also for the wellbeing of your close relatives, who may share hereditary risk factors.
Why is Genetic Testing Important for Pancreatic Cancer?
Pancreatic cancer is often diagnosed at a late stage, which can make it more difficult to treat. Identifying inherited risk early allows for proactive screening and, in some cases, risk-reducing strategies. For individuals already diagnosed, genetic information may influence treatment decisions, particularly when considering eligibility for targeted therapies.
Additionally, a genetic diagnosis can guide testing for family members, enabling them to take preventative steps if necessary.
How our Genetic Testing for Pancreatic Cancer Works
The process begins with a personalised consultation where your consultant reviews your personal and family cancer history. If appropriate, you’ll be offered a saliva or blood collection kit. Many patients choose the convenience of an at-home saliva test, which is sent to our accredited lab in a pre-paid envelope.
Your sample is analysed to look for mutations in genes associated with pancreatic cancer. Results typically take 2 to 4 weeks, after which you will receive a detailed report and follow-up consultation. Your consultant will explain the findings clearly and offer tailored guidance on what they mean for you and your family.
We also work in partnership with clinical geneticists and specialist teams to ensure that your care is cohesive and guided fully by your results.
Who Should Consider Genetic Testing for Pancreatic Cancer?
You may wish to consider testing if:
- You have a personal or family history of pancreatic cancer
- A relative has been diagnosed with pancreatic cancer before age 50
- You have a family history of multiple related cancers, including breast, ovarian or colorectal cancer
- There is a known mutation in a pancreatic cancer gene in your family
- You are of Ashkenazi Jewish ancestry, which is linked to higher prevalence of certain mutations
Even without a strong family history, testing may be appropriate in some clinical situations. Your consultant will help assess whether testing is right for you.
Which Genes are Tested?
Commonly tested genes include BRCA1, BRCA2, PALB2, ATM, CDKN2A, and STK11, among others. These genes are involved in DNA repair and tumour suppression, and mutations in them are associated with higher risk of pancreatic and other cancers.
Depending on your history, broader panels may be recommended to check for other hereditary cancer syndromes.
What Proportion of Pancreatic Cancers are Hereditary?
Approximately 5 to 10% of pancreatic cancers are thought to be hereditary, caused by inherited gene mutations. However, identifying these cases is crucial, as they may respond differently to certain treatments and carry future implications for family members.
Genetic testing helps pinpoint these inherited cases so that care can be more closely targeted and preventative strategies can be shared with relatives.
Genetic Testing for Pancreatic Cancer FAQs
- Is genetic testing painful?
No. Testing involves a simple blood or saliva sample and is completely non-invasive.
- Can I do the test from home?
Yes, our service is fully home-based. We will send you a simple saliva collection kit, which you return to the laboratory in a prepaid envelope.
- How long does it take to get the results?
Results are typically available within 4–6 weeks. A detailed report will be sent to you directly.
- What can genetic testing tell me about my health?
It can identify genetic markers linked to certain inherited conditions, offering insights into your risk and helping guide treatment or preventive care.
- Who should consider genetic testing?
Anyone with a family history of genetic disorders or certain cancers, or those looking for personalised insights into long-term health, fertility, or wellness.
- If my test is positive, does it mean I will get cancer?
No. A positive result means you have a higher risk, but it does not guarantee that you will develop cancer. It provides valuable information to guide screening, prevention and treatment decisions.
- What if my results show a genetic mutation?
You’ll receive expert support and a personalised care plan. This may include enhanced screening, preventive strategies or referrals for family members to consider testing.
Why Choose The Forbury Clinic?
The Forbury Clinic provides private genetic testing with accuracy, efficiency and patient comfort in mind. Our expert clinicians use the latest diagnostic technology to ensure reliable results, helping you to understand your body and take control of your health. We prioritise a smooth experience with minimal waiting times, allowing for fast testing and efficient result processing.